David A. Sinclair




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Ageing is a natural and inevitable part of life: we all grow old sooner or later, and there is nothing we can do about it; but what if this were not the case? Dr David Sinclair has based his entire career, as well as his book, Lifespan: Why We Age - And Why We Don't Have To, on the theory that the very opposite is true: he maintains that old age is a disease, and as such, it can, and must, be treated. Sinclair describes the biological reasons why we age, but more importantly, explains what we can do to slow down and even reverse this process. The book takes us through a thorough analysis of the ethical, social, economic, and political implications of humans living up to 120 years of age, and underlines the importance of achieving this objective while maintaining our physical and mental health.

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Analysis and key concepts


Growing old is not inevitable: it is a disease that can be treated


“Information Theory of Aging”: we age due to a lack of cellular information


We can prolong our lives by making sure our bodies maintain ‘good stress’ levels


Science and medicine are working to slow down, and even reverse, ageing


It could be a real advantage for our planet if more people could live longer lives


We have to take responsibility if we want to live a longer and healthier life




Take-home message

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Many useful tips to:

  • Discover the biological reasons behind ageing.
  • Realise that old age is not inevitable, but a disease that can, and must, be treated.
  • Learn about the current methods to treat old age, and the technology that will become available in the near future.

David A. Sinclair was born in Australia, and now lives in Boston, in the United States, where he is a professor of genetics at Harvard Medical School. He is widely recognised as one of the greatest innovators of his generation; Time Magazine named him one of the 100 most influential people in the world in 2014, and one of the 50 most influential people in healthcare in 2018. He is a board member of the American Federation for Aging Research, has received more than 35 awards for his scientific research, and has appeared in numerous scientific and general interest magazines, such as The New York Times, The Washington Post and The Economist.

Publishing house:

Harper Thorsons